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Chemical structure of [Asn670, Sta671, Val672]-Amyloid beta Peptide (662-675)

GA20041

[Asn670, Sta671, Val672]-Amyloid beta Peptide (662-675)

Also listed as (Asn⁶⁷⁰,Sta⁶⁷¹,Val⁶⁷²)-Amyloid β/A4 Protein Precursor₇₇₀ (662-675)

Amyloid precursor protein (APP) β-secretase from human brain cleaves full-length APP at the amino terminus of the amyloid β-protein (Aβ) sequence, thus leading to the generation and extracellular release of β-cleaved soluble APP and a corresponding cell-associated carboxy-terminal fragment· The subsequent cleavage of the C-terminal fragment by γ-secretase(s) leads to the formation of Aβ· This new peptide represents a potent substrate analog inhibitor of APP β-secretase with IC?? = 30 nM

ChemicalCAS350228-37-4MW1651.83FormulaC73H118N16O27
CAS number
350228-37-4
Molecular weight
1651.83
Formula
C73H118N16O27
Solubility
Soluble in DMSO
InChIKey
CQTBDEGWLSDJEP-UHFFFAOYSA-N
Catalogue number
GA20041
Brand
GLPBIO
Computed properties PubChem CID 44135344 · XLogP -8.6 · TPSA 721 Ų · H-bond donors 24
XLogP
-8.6
TPSA
721 Ų
H-bond donors
24
H-bond acceptors
29
Rotatable bonds
57
Heavy atoms
116

SMILES CCC(C)C(C(=O)NC(CO)C(=O)NC(CCC(=O)O)C(=O)NC(C(C)C)C(=O)NC(CC(=O)N)C(=O)NC(CC(C)C)C(CC(=O)NC(C(C)C)C(=O)NC(C)C(=O)NC(CCC(=O)O)C(=O)NC(CC1=CC=CC=C1)C(=O)O)O)NC(=O)C(CCC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(C(C)O)NC(=O)C(CCCCN)N

Computed descriptors from PubChem (CID 44135344), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.