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Chemical structure of NBI 27914

GF05870

NBI 27914

Also known as 5-chloro-4-N-(cyclopropylmethyl)-2-methyl-4-N-propyl-6-N-(2,4,6-trichlorophenyl)pyrimidine-4,6-diamine

NBI-27914 is a potent and selective antagonist of CRFR1· The CRF receptors, CRFR1 and CRFR2, are members of the G protein-coupled receptor superfamily

ChemicalCAS184241-44-9MW434.19FormulaC18H20Cl4N4
CAS number
184241-44-9
Molecular weight
434.19
Formula
C18H20Cl4N4
Solubility
DMSO : 100 mg/mL (230·31 mM; Need ultrasonic)
InChIKey
KNADXBVKFAUMCR-UHFFFAOYSA-N
Catalogue number
GF05870
Brand
GLPBIO
Computed properties PubChem CID 176157 · XLogP 7.1 · TPSA 41.1 Ų · H-bond donors 1
XLogP
7.1
TPSA
41.1 Ų
H-bond donors
1
H-bond acceptors
4
Rotatable bonds
7
Heavy atoms
26

SMILES CCCN(CC1CC1)C2=NC(=NC(=C2Cl)NC3=C(C=C(C=C3Cl)Cl)Cl)C

Computed descriptors from PubChem (CID 176157), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.