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Chemical structure of NBI-42902

GC70777

NBI-42902

Also known as 3-[(2R)-2-amino-2-phenylethyl]-1-[(2,6-difluorophenyl)methyl]-5-(2-fluoro-3-methoxyphenyl)-6-methylpyrimidine-2,4-dione

NBI-42902 is an orally active, potent functional and competitive antagonist of GnRH receptor with an IC50 value of 0·79 nM, a Ki value of 0·56 nM, respectively

ChemicalCAS352290-60-9MW495.49FormulaC27H24F3N3O3
CAS number
352290-60-9
Molecular weight
495.49
Formula
C27H24F3N3O3
Solubility
DMSO : 100 mg/mL (201·82 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
InChIKey
CJUWBZDJMYYRDG-QFIPXVFZSA-N
Catalogue number
GC70777
Brand
GLPBIO
Computed properties PubChem CID 11167850 · XLogP 3.8 · TPSA 75.9 Ų · H-bond donors 1
XLogP
3.8
TPSA
75.9 Ų
H-bond donors
1
H-bond acceptors
7
Rotatable bonds
7
Heavy atoms
36

SMILES CC1=C(C(=O)N(C(=O)N1CC2=C(C=CC=C2F)F)C[C@@H](C3=CC=CC=C3)N)C4=C(C(=CC=C4)OC)F

Computed descriptors from PubChem (CID 11167850), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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