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Chemical structure of PROTAC BRD4 Degrader-12

GF04063

PROTAC BRD4 Degrader-12

Also known as [(3R,5S)-1-[(2S)-2-[11-[[8-(3,5-difluoro-2-pyridinyl)-15-methyl-4-(methylsulfonylmethyl)-14-oxo-8,12,15-triazatetracyclo[8.6.1.02,7.013,17]heptadeca-1(16),2(7),3,5,10,13(17)-hexaene-5-carbonyl]amino]undecanoylamino]-3,3-dimethylbutanoyl]-5-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methylcarbamoyl]pyrrolidin-3-yl] 3-methylsulfonylsulfanylbutan-2-yl carbonate

PROTAC BRD4 Degrader-12 (catalogue number GF04063) is a research-grade chemical available from LABO Scientific in Israel, CAS registry number 2417370-90-0. Molecular formula C62H77F2N9O12S4, molecular weight 1306.58. IUPAC name: [(3R,5S)-1-[(2S)-2-[11-[[8-(3,5-difluoro-2-pyridinyl)-15-methyl-4-(methylsulfonylmethyl)-14-oxo-8,12,15-triazatetracyclo[8.6.1.02,7.013,17]heptadeca-1(16),2(7),3,5,10,13(17)-hexaene-5-carbonyl]amino]undecanoylamino]-3,3-dimethylbutanoyl]-5-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methylcarbamoyl]pyrrolidin-3-yl] 3-methylsulfonylsulfanylbutan-2-yl carbonate. Supplied in 2 pack sizes, from 1mg at ₪1,264.46 to 5mg at ₪3,671.02; the final price is confirmed on your quote, and the lot certificate of analysis and safety data sheet are emailed with your order confirmation.

ChemicalCAS2417370-90-0MW1306.58FormulaC62H77F2N9O12S4
CAS number
2417370-90-0
Molecular weight
1306.58
Formula
C62H77F2N9O12S4
InChIKey
RTGMFKZUBIYNLA-TXWUOVCNSA-N
Catalogue number
GF04063
Brand
GLPBIO
Computed properties PubChem CID 162642591 · XLogP 8.4 · TPSA 347 Ų · H-bond donors 4
XLogP
8.4
TPSA
347 Ų
H-bond donors
4
H-bond acceptors
19
Rotatable bonds
29
Heavy atoms
89

SMILES CC1=C(SC=N1)C2=CC=C(C=C2)CNC(=O)[C@@H]3C[C@H](CN3C(=O)[C@H](C(C)(C)C)NC(=O)CCCCCCCCCCNC(=O)C4=CC5=C(C=C4CS(=O)(=O)C)C6=CN(C(=O)C7=C6C(=CN7)CN5C8=C(C=C(C=N8)F)F)C)OC(=O)OC(C)C(C)SS(=O)(=O)C

Computed descriptors from PubChem (CID 162642591), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.