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Chemical structure of JY-2

GD96632

JY-2

Also known as 5-(2,4-dichlorophenyl)-3-pyridin-2-yl-1,2,4-oxadiazole

JY-2 is a moderately selective FoxO1 inhibitor with IC50 of 22μM, JY-2 has moderate inhibitory effect on FoxO3a and FoxO4 too

ChemicalCAS339103-05-8MW292.12FormulaC13H7Cl2N3O
CAS number
339103-05-8
Molecular weight
292.12
Formula
C13H7Cl2N3O
Solubility
80mg/mL in DMSO (ultrasonic and warming and heat to 60°C)
InChIKey
WBMHQMQALJDGHI-UHFFFAOYSA-N
Catalogue number
GD96632
Brand
GLPBIO
Computed properties PubChem CID 702923 · XLogP 3.3 · TPSA 51.8 Ų · H-bond donors 0
XLogP
3.3
TPSA
51.8 Ų
H-bond donors
0
H-bond acceptors
4
Rotatable bonds
2
Heavy atoms
19

SMILES C1=CC=NC(=C1)C2=NOC(=N2)C3=C(C=C(C=C3)Cl)Cl

Computed descriptors from PubChem (CID 702923), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.