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Chemical structure of YHS-12

GC92072

YHS-12

Also known as (E)-N,N'-bis[2-(didodecylamino)ethyl]but-2-enediamide

YHS-12 is an ionizable cationic lipid (pKa = 6·506) that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of siRNA and mRNA in vitro and in vivo

ChemicalCAS2959463-68-2MW873.5FormulaC56H112N4O2
CAS number
2959463-68-2
Molecular weight
873.5
Formula
C56H112N4O2
Solubility
Chloroform： Sparingly soluble： 1–10 mg/ml,Methanol： Slightly soluble： 0·1–1 mg/ml
InChIKey
PHYKVTFJFHNIHG-XVIFHXHVSA-N
Catalogue number
GC92072
Brand
GLPBIO
Computed properties PubChem CID 172195219 · XLogP 21.5 · TPSA 64.7 Ų · H-bond donors 2
XLogP
21.5
TPSA
64.7 Ų
H-bond donors
2
H-bond acceptors
4
Rotatable bonds
52
Heavy atoms
62

SMILES CCCCCCCCCCCCN(CCCCCCCCCCCC)CCNC(=O)/C=C/C(=O)NCCN(CCCCCCCCCCCC)CCCCCCCCCCCC

Computed descriptors from PubChem (CID 172195219), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.