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Chemical structure of YH-306

GC64992

YH-306

Also known as 2-(4-hydroxyphenyl)-1-(1,3,4,9-tetrahydropyrido[3,4-b]indol-2-yl)ethanone

YH-306 is an antitumor agent· YH-306 suppresses colorectal tumour growth and metastasis via FAK pathway· YH-306 significantly inhibits the migration and invasion of colorectal cancer cells· YH-306 potently suppresses uninhibited proliferation and induces cell apoptosis· YH-306 suppresses the activation of FAK, c-Src, paxillin, and PI3K, Rac1 and the expression of MMP2 and MMP9· YH-306 also inhibita actin-related protein (Arp2/3) complex-mediated actin polymerization

ChemicalCAS1373764-75-0MW306.36FormulaC19H18N2O2
CAS number
1373764-75-0
Molecular weight
306.36
Formula
C19H18N2O2
Solubility
DMSO ： 20 mg/mL (65·28 mM; ultrasonic and adjust pH to 1 with HCl)
InChIKey
WFTJZQLEQGPZBC-UHFFFAOYSA-N
Catalogue number
GC64992
Brand
GLPBIO
Computed properties PubChem CID 60162063 · XLogP 2.7 · TPSA 56.3 Ų · H-bond donors 2
XLogP
2.7
TPSA
56.3 Ų
H-bond donors
2
H-bond acceptors
2
Rotatable bonds
2
Heavy atoms
23

SMILES C1CN(CC2=C1C3=CC=CC=C3N2)C(=O)CC4=CC=C(C=C4)O

Computed descriptors from PubChem (CID 60162063), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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