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Chemical structure of TG46

GC91689

TG46

Also known as N-tert-butyl-3-[[5-methyl-2-[4-(morpholin-4-ylmethyl)anilino]pyrimidin-4-yl]amino]benzenesulfonamide

TG46 is an inhibitor of JAK2 (IC50 = 12·5 µM)

ChemicalCAS936091-15-5MW510.7FormulaC26H34N6O3S
CAS number
936091-15-5
Molecular weight
510.7
Formula
C26H34N6O3S
Solubility
DMSO： Soluble： ≥10 mg/ml,Ethanol： Slightly Soluble： 0·1–1 mg/ml
InChIKey
MMXZBJJTHQWMEN-UHFFFAOYSA-N
Catalogue number
GC91689
Brand
GLPBIO
Computed properties PubChem CID 16722834 · XLogP 3.7 · TPSA 117 Ų · H-bond donors 3
XLogP
3.7
TPSA
117 Ų
H-bond donors
3
H-bond acceptors
9
Rotatable bonds
9
Heavy atoms
36

SMILES CC1=CN=C(N=C1NC2=CC(=CC=C2)S(=O)(=O)NC(C)(C)C)NC3=CC=C(C=C3)CN4CCOCC4

Computed descriptors from PubChem (CID 16722834), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.