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Chemical structure of TG6-10-1

GC19354

TG6-10-1

Also known as (E)-N-[2-[2-(trifluoromethyl)indol-1-yl]ethyl]-3-(3,4,5-trimethoxyphenyl)prop-2-enamide

TG6-10-1 is an EP2 antagonist, shows low-nanomolar antagonist activity against only EP2, >300-fold selectivity over human EP3, EP4, and IP receptors, 100-fold selectivity over EP1 receptors

ChemicalCAS1415716-58-3MW448.43FormulaC23H23F3N2O4
CAS number
1415716-58-3
Molecular weight
448.43
Formula
C23H23F3N2O4
Solubility
DMSO : ≥ 100 mg/mL (223·00 mM)
InChIKey
WUYOECAJFJFUFC-CMDGGOBGSA-N
Catalogue number
GC19354
Brand
GLPBIO
Computed properties PubChem CID 71499384 · XLogP 4.2 · TPSA 61.7 Ų · H-bond donors 1
XLogP
4.2
TPSA
61.7 Ų
H-bond donors
1
H-bond acceptors
7
Rotatable bonds
8
Heavy atoms
32

SMILES COC1=CC(=CC(=C1OC)OC)/C=C/C(=O)NCCN2C3=CC=CC=C3C=C2C(F)(F)F

Computed descriptors from PubChem (CID 71499384), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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