Loading...
Chemical structure of MAT-POS-e194df51-1

GC75643

MAT-POS-e194df51-1

Also known as (4S)-6-chloro-2-[(1-cyanocyclopropyl)methylsulfonyl]-N-isoquinolin-4-yl-3,4-dihydro-1H-isoquinoline-4-carboxamide

MAT-POS-e194df51-1 is an orally active, non-covalent and non-peptide SARS-CoV-2 main protease (Mpro) inhibitor with an IC50 value of 37nM

ChemicalCAS2765433-05-2MW480.97FormulaC24H21ClN4O3S
CAS number
2765433-05-2
Molecular weight
480.97
Formula
C24H21ClN4O3S
Solubility
DMSO： 100 mg/mL (207·91 mM; ultrasonic and warming and heat to 60°C)
InChIKey
YAYDSAMHSQCKIM-OAQYLSRUSA-N
Catalogue number
GC75643
Brand
GLPBIO
Computed properties PubChem CID 156906151 · XLogP 2.4 · TPSA 112 Ų · H-bond donors 1
XLogP
2.4
TPSA
112 Ų
H-bond donors
1
H-bond acceptors
6
Rotatable bonds
5
Heavy atoms
33

SMILES C1CC1(CS(=O)(=O)N2C[C@H](C3=C(C2)C=CC(=C3)Cl)C(=O)NC4=CN=CC5=CC=CC=C54)C#N

Computed descriptors from PubChem (CID 156906151), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.