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Chemical structure of MAX-10181

GC69677

MAX-10181

Also known as 2-[[3-[(E)-2-[3-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-methylphenyl]ethenyl]-4-(trifluoromethyl)phenyl]methylamino]-3-hydroxy-2-methylpropanoic acid

MAX-10181 (PD-1/PD-L1-IN-30) is a PD-1/PD-L1 binding inhibitor with an IC50 value of 0·018 μM· MAX-10181 can be used for research on cancer and other related diseases

ChemicalCAS2171558-14-6MW527.53FormulaC29H28F3NO5
CAS number
2171558-14-6
Molecular weight
527.53
Formula
C29H28F3NO5
InChIKey
PTGUEPRQUFAZLN-BQYQJAHWSA-N
Catalogue number
GC69677
Brand
GLPBIO
Computed properties PubChem CID 138632287 · XLogP 3 · TPSA 88 Ų · H-bond donors 3
XLogP
3
TPSA
88 Ų
H-bond donors
3
H-bond acceptors
9
Rotatable bonds
8
Heavy atoms
38

SMILES CC1=C(C=CC=C1C2=CC3=C(C=C2)OCCO3)/C=C/C4=C(C=CC(=C4)CNC(C)(CO)C(=O)O)C(F)(F)F

Computed descriptors from PubChem (CID 138632287), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.