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Chemical structure of JBSNF-000028 free base

GC75452

JBSNF-000028 free base

Also known as 10-methyl-1,10-diazatricyclo[6.3.1.04,12]dodeca-4(12),5,7-trien-11-imine

JBSNF-000028 is an orally active nicotinamide N-methyltransferase (NNMT) inhibitor with IC50s of 0·033 ?M, 0·19 ?M and 0·21 ?M against human NNMT (hNNMT), monkey NNMT (mkNNMT), and mouse NNMT (mNNMT), respectively

ChemicalCAS3026599-90-3MW187.24FormulaC11H13N3
CAS number
3026599-90-3
Molecular weight
187.24
Formula
C11H13N3
Solubility
DMSO： 60 mg/mL (320·44 mM; Need ultrasonic)
InChIKey
QHQIGFVXRSNTKN-UHFFFAOYSA-N
Catalogue number
GC75452
Brand
GLPBIO
Computed properties PubChem CID 163321811 · XLogP 1 · TPSA 30.3 Ų · H-bond donors 1
XLogP
1
TPSA
30.3 Ų
H-bond donors
1
H-bond acceptors
1
Rotatable bonds
0
Heavy atoms
14

SMILES CN1CC2=CC=CC3=C2N(C1=N)CC3

Computed descriptors from PubChem (CID 163321811), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.