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Chemical structure of KB-5492 free base

GC65178

KB-5492 free base

Also known as (4-methoxyphenyl) 2-[4-[(3,4,5-trimethoxyphenyl)methyl]piperazin-1-yl]acetate

KB-5492 free base is a potent and selective inhibitor of sigma receptor, inhibits specific [3H]1,3-di(2-tolyl)guanidine (DTG) binding to the sigma receptor with an IC50 of 3·15 μM

ChemicalCAS113594-64-2MW430.49FormulaC23H30N2O6
CAS number
113594-64-2
Molecular weight
430.49
Formula
C23H30N2O6
Solubility
DMSO : 100 mg/mL (232·29 mM; Need ultrasonic)
InChIKey
RVYZAZTXLLAVGZ-UHFFFAOYSA-N
Catalogue number
GC65178
Brand
GLPBIO
Computed properties PubChem CID 131083 · XLogP 2.9 · TPSA 69.7 Ų · H-bond donors 0
XLogP
2.9
TPSA
69.7 Ų
H-bond donors
0
H-bond acceptors
8
Rotatable bonds
10
Heavy atoms
31

SMILES COC1=CC=C(C=C1)OC(=O)CN2CCN(CC2)CC3=CC(=C(C(=C3)OC)OC)OC

Computed descriptors from PubChem (CID 131083), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Documents
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