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Chemical structure of CHMFL-PI4K-127

GC75436

CHMFL-PI4K-127

Also known as 5-[5-(benzenesulfonamido)-6-chloro-3-pyridinyl]-N-methylpyridine-3-carboxamide

CHMFL-PI4K-127 (compound 15g) is an orally active, potent and high selective PfPI4K (Plasmodium falciparum PI4K kinase) inhibitor, with an IC50 of 0·9 nM

ChemicalCAS2377604-81-2MW402.85FormulaC18H15ClN4O3S
CAS number
2377604-81-2
Molecular weight
402.85
Formula
C18H15ClN4O3S
Solubility
DMSO： 125 mg/mL (310·29 mM; Need ultrasonic)
InChIKey
IHWSJFBJORCEAK-UHFFFAOYSA-N
Catalogue number
GC75436
Brand
GLPBIO
Computed properties PubChem CID 141754964 · XLogP 2.2 · TPSA 109 Ų · H-bond donors 2
XLogP
2.2
TPSA
109 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
5
Heavy atoms
27

SMILES CNC(=O)C1=CN=CC(=C1)C2=CC(=C(N=C2)Cl)NS(=O)(=O)C3=CC=CC=C3

Computed descriptors from PubChem (CID 141754964), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.