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Chemical structure of PROTAC eEF2K degrader-1

GC75313

PROTAC eEF2K degrader-1

Also known as 7-amino-3-[2-[2-[2-[[2-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]oxyacetyl]amino]ethoxy]ethylamino]-2-oxoethyl]-1-ethyl-2,4-dioxopyrido[2,3-d]pyrimidine-6-carboxamide

PROTAC eEF2K degrader-1 (Compound 11l) is an eEF2K-Targeting PROTAC small molecule that induces apoptosis in MDA-MB-231 cells

ChemicalCAS2458170-54-0MW707.65FormulaC31H33N9O11
CAS number
2458170-54-0
Molecular weight
707.65
Formula
C31H33N9O11
Solubility
DMSO： 25 mg/mL (35·33 mM; ultrasonic and warming and heat to 60°C)
InChIKey
WEFNUHQNBKXKGD-UHFFFAOYSA-N
Catalogue number
GC75313
Brand
GLPBIO
Computed properties PubChem CID 164516877 · XLogP -2.1 · TPSA 283 Ų · H-bond donors 5
XLogP
-2.1
TPSA
283 Ų
H-bond donors
5
H-bond acceptors
13
Rotatable bonds
14
Heavy atoms
51

SMILES CCN1C2=NC(=C(C=C2C(=O)N(C1=O)CC(=O)NCCOCCNC(=O)COC3=CC=CC4=C3C(=O)N(C4=O)C5CCC(=O)NC5=O)C(=O)N)N

Computed descriptors from PubChem (CID 164516877), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.