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Chemical structure of AZ3976

GC74956

AZ3976

Also known as tert-butyl 3-[(4-oxo-3H-pyrido[2,3-d]pyrimidin-2-yl)amino]azetidine-1-carboxylate

AZ3976 is a potent plasminogen activator inhibitor type 1 (PAI-1) inhibitor with an IC50 value of 26 μM in an enzymatic chromogenic assay

ChemicalCAS1418747-15-5MW317.34FormulaC15H19N5O3
CAS number
1418747-15-5
Molecular weight
317.34
Formula
C15H19N5O3
Solubility
DMSO: 100 mg/mL (315·12 mM; Need ultrasonic)
InChIKey
CKUDSTVQYFRZJW-UHFFFAOYSA-N
Catalogue number
GC74956
Brand
GLPBIO
Computed properties PubChem CID 135566649 · XLogP 0.5 · TPSA 95.9 Ų · H-bond donors 2
XLogP
0.5
TPSA
95.9 Ų
H-bond donors
2
H-bond acceptors
5
Rotatable bonds
4
Heavy atoms
23

SMILES CC(C)(C)OC(=O)N1CC(C1)NC2=NC3=C(C=CC=N3)C(=O)N2

Computed descriptors from PubChem (CID 135566649), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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Pricing
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Documents
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