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Chemical structure of FRM-024

GC74920

FRM-024

Also known as (5R,6S)-5-(4-chlorophenyl)-6-cyclopropyl-3-[6-methoxy-5-(4-methylimidazol-1-yl)-2-pyridinyl]-5,6-dihydro-2H-1,2,4-oxadiazine

FRM-024 is a potent CNS-penetrant gamma secretase modulator for familial Alzheimer’s disease

ChemicalCAS2085780-87-4MW423.9FormulaC22H22ClN5O2
CAS number
2085780-87-4
Molecular weight
423.9
Formula
C22H22ClN5O2
Solubility
DMSO： 100 mg/mL (235·90 mM; Need ultrasonic)
InChIKey
IOQORVDNYPOZPL-UXHICEINSA-N
Catalogue number
GC74920
Brand
GLPBIO
Computed properties PubChem CID 126599752 · XLogP 3.8 · TPSA 73.6 Ų · H-bond donors 1
XLogP
3.8
TPSA
73.6 Ų
H-bond donors
1
H-bond acceptors
5
Rotatable bonds
5
Heavy atoms
30

SMILES CC1=CN(C=N1)C2=C(N=C(C=C2)C3=N[C@@H]([C@@H](ON3)C4CC4)C5=CC=C(C=C5)Cl)OC

Computed descriptors from PubChem (CID 126599752), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.