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Chemical structure of FR-167356

GC70544

FR-167356

Also known as 2,6-dichloro-N-[3-(2-hydroxypropan-2-yl)-2-methyl-1-benzofuran-7-yl]benzamide

FR-167356 is a potent, orally active and selective vacuolar ATPase inhibitor with IC50 values of 170, 220, 370, and 1200 nM for osteoclast plasma membranes, macrophage microsomes, renal brush border membranes, and liver lysosomal membranes, respectively

ChemicalCAS174185-16-1MW378.25FormulaC19H17Cl2NO3
CAS number
174185-16-1
Molecular weight
378.25
Formula
C19H17Cl2NO3
InChIKey
GCAOVMKRBUCSET-UHFFFAOYSA-N
Catalogue number
GC70544
Brand
GLPBIO
Computed properties PubChem CID 10068207 · XLogP 4.5 · TPSA 62.5 Ų · H-bond donors 2
XLogP
4.5
TPSA
62.5 Ų
H-bond donors
2
H-bond acceptors
3
Rotatable bonds
3
Heavy atoms
25

SMILES CC1=C(C2=C(O1)C(=CC=C2)NC(=O)C3=C(C=CC=C3Cl)Cl)C(C)(C)O

Computed descriptors from PubChem (CID 10068207), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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