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Chemical structure of SB 220025

GC74862

SB 220025

Also known as 4-[5-(4-fluorophenyl)-3-piperidin-4-ylimidazol-4-yl]pyrimidin-2-amine

SB 220025 is a reversible, orally active, cell-permeable, ATP-competitive and selective human p38 MAPK inhibitor (IC50 = 60 nM)

ChemicalCAS165806-53-1MW338.38FormulaC18H19FN6
CAS number
165806-53-1
Molecular weight
338.38
Formula
C18H19FN6
Solubility
DMSO： 50 mg/mL (147·76 mM; ultrasonic and warming and heat to 60°C)
InChIKey
VSPFURGQAYMVAN-UHFFFAOYSA-N
Catalogue number
GC74862
Brand
GLPBIO
Computed properties PubChem CID 5164 · XLogP 1.4 · TPSA 81.7 Ų · H-bond donors 2
XLogP
1.4
TPSA
81.7 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
3
Heavy atoms
25

SMILES C1CNCCC1N2C=NC(=C2C3=NC(=NC=C3)N)C4=CC=C(C=C4)F

Computed descriptors from PubChem (CID 5164), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.