Loading...
Chemical structure of SB 216763

GC10463

SB 216763

Also known as 3-(2,4-dichlorophenyl)-4-(1-methylindol-3-yl)pyrrole-2,5-dione

SB 216763 stands out as a powerful, selective, and ATP-competitive inhibitor of GSK-3, effectively targeting both GSK-3α and GSK-3β with an impressive IC50 of 34·3 nM[1-3]

ChemicalCAS280744-09-4MW371.22FormulaC19H12Cl2N2O2
CAS number
280744-09-4
Molecular weight
371.22
Formula
C19H12Cl2N2O2
Solubility
≥ 56·8mg/mL in DMSO
InChIKey
JCSGFHVFHSKIJH-UHFFFAOYSA-N
Catalogue number
GC10463
Brand
GLPBIO
Computed properties PubChem CID 176158 · XLogP 3.9 · TPSA 51.1 Ų · H-bond donors 1
XLogP
3.9
TPSA
51.1 Ų
H-bond donors
1
H-bond acceptors
2
Rotatable bonds
2
Heavy atoms
25

SMILES CN1C=C(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=C(C=C(C=C4)Cl)Cl

Computed descriptors from PubChem (CID 176158), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.