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Chemical structure of Gefapixant citrate

GC74751

Gefapixant citrate

Also known as 5-(2,4-diaminopyrimidin-5-yl)oxy-2-methoxy-4-propan-2-ylbenzenesulfonamide;2-hydroxypropane-1,2,3-tricarboxylic acid

Gefapixant citrate is an orally active and potent purinergic P2X3 receptor (P2X3R) antagonist, with IC50 values of ~30 nM versus recombinant hP2X3 homotrimers and 100-250 nM at hP2X2/3 heterotrimeric receptors

ChemicalCAS2310299-91-1MW545.52FormulaC20H27N5O11S
CAS number
2310299-91-1
Molecular weight
545.52
Formula
C20H27N5O11S
Solubility
DMSO： 350 mg/mL (641·59 mM; Need ultrasonic)
InChIKey
AIJVJYUOMCRFOE-UHFFFAOYSA-N
Catalogue number
GC74751
Brand
GLPBIO
Computed properties PubChem CID 145720531 · TPSA 297 Ų · H-bond donors 7 · H-bond acceptors 16
TPSA
297 Ų
H-bond donors
7
H-bond acceptors
16
Rotatable bonds
10
Heavy atoms
37

SMILES CC(C)C1=CC(=C(C=C1OC2=CN=C(N=C2N)N)S(=O)(=O)N)OC.C(C(=O)O)C(CC(=O)O)(C(=O)O)O

Computed descriptors from PubChem (CID 145720531), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.