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Chemical structure of Gefitinib

GC16737

Gefitinib

Also listed as Gefitinib (ZD1839)

Gefitinib (ZD1839), is a potent EGFR-TKI (EGFR tyrosine kinase inhibitor) with IC50 of 0·033 µM, selectively inhibits EGF-stimulated tumor cell growth with IC50 of 0·054 µM and that blocks EGF-stimulated EGFR (epidermal growth factor receptor) autophosphorylation in tumor cells

ChemicalCAS184475-35-2MW446.9FormulaC22H24ClFN4O3
CAS number
184475-35-2
Molecular weight
446.9
Formula
C22H24ClFN4O3
Solubility
≥ 22·3mg/mL in DMSO, ≥ 2·48 mg/mL in EtOH with ultrasonic
InChIKey
XGALLCVXEZPNRQ-UHFFFAOYSA-N
Catalogue number
GC16737
Brand
GLPBIO
Computed properties PubChem CID 123631 · XLogP 4.1 · TPSA 68.7 Ų · H-bond donors 1
XLogP
4.1
TPSA
68.7 Ų
H-bond donors
1
H-bond acceptors
8
Rotatable bonds
8
Heavy atoms
31

SMILES COC1=C(C=C2C(=C1)N=CN=C2NC3=CC(=C(C=C3)F)Cl)OCCCN4CCOCC4

Computed descriptors from PubChem (CID 123631), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.