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Chemical structure of FT-FAPI-12_9

GC74072

FT-FAPI-12_9

Also known as N-[2-[(2S)-2-cyano-4,4-difluoropyrrolidin-1-yl]-2-oxoethyl]-6-[methyl(3-piperazin-1-ylpropyl)amino]quinoline-4-carboxamide

FT-FAPI-12_9 is a FAP-binding moiety, which can be used for synthesis of FAP-targeted radiotracer FAPI-46

ChemicalCAS2883407-81-4MW499.56FormulaC25H31F2N7O2
CAS number
2883407-81-4
Molecular weight
499.56
Formula
C25H31F2N7O2
Solubility
DMSO : 125 mg/mL (250·22 mM; Need ultrasonic and warming)
InChIKey
KAZYDEMPAXZEJT-IBGZPJMESA-N
Catalogue number
GC74072
Brand
GLPBIO
Computed properties PubChem CID 168268390 · XLogP 1.5 · TPSA 105 Ų · H-bond donors 2
XLogP
1.5
TPSA
105 Ų
H-bond donors
2
H-bond acceptors
9
Rotatable bonds
8
Heavy atoms
36

SMILES CN(CCCN1CCNCC1)C2=CC3=C(C=CN=C3C=C2)C(=O)NCC(=O)N4CC(C[C@H]4C#N)(F)F

Computed descriptors from PubChem (CID 168268390), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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