GC74050
PROTAC CDK4/6 degrader 1
Also known as 5-[4-[4-[(8-cyclopentyl-7-oxopteridin-2-yl)amino]phenyl]piperazin-1-yl]-N-[2-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]ethyl]pentanamide
PROTAC CDK4/6 degrader 1 (Compound 7f) is a dual degrader for CDK4 and CDK6 with DC50 of 10·5 and 2·5 nM
ChemicalCAS3025082-14-5MW789.88FormulaC41H47N11O6
- CAS number
- 3025082-14-5
- Molecular weight
- 789.88
- Formula
- C41H47N11O6
- Solubility
- DMSO ： 100 mg/mL (126·60 mM; Need ultrasonic)
- InChIKey
- ITSRILWBOAUMKU-UHFFFAOYSA-N
- Catalogue number
- GC74050
- Brand
- GLPBIO
Computed properties PubChem CID 172419466 · XLogP 3 · TPSA 202 Ų · H-bond donors 4
- XLogP
- 3
- TPSA
- 202 Ų
- H-bond donors
- 4
- H-bond acceptors
- 13
- Rotatable bonds
- 14
- Heavy atoms
- 58
SMILES C1CCC(C1)N2C(=O)C=NC3=CN=C(N=C32)NC4=CC=C(C=C4)N5CCN(CC5)CCCCC(=O)NCCNC6=CC=CC7=C6C(=O)N(C7=O)C8CCC(=O)NC8=O
Computed descriptors from PubChem (CID 172419466), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il