GC73998
MK-1084
Also known as 19-chloro-22-[(2S,5R)-2,5-dimethyl-4-prop-2-enoylpiperazin-1-yl]-13,16-difluoro-3-propan-2-yl-8,11-dioxa-1,4,23,26-tetrazapentacyclo[16.6.2.02,7.012,17.021,25]hexacosa-2(7),3,5,12,14,16,18,20,22,25-decaen-24-one
MK-1084 is a selective KRAS G12C inhibitor that is currently in Phase I clinical trial (NCT05067283)
ChemicalCAS2641216-67-1MW637.08FormulaC32H31ClF2N6O4
- CAS number
- 2641216-67-1
- Molecular weight
- 637.08
- Formula
- C32H31ClF2N6O4
- Solubility
- DMSO ： 100 mg/mL (156·97 mM; Need ultrasonic)
- InChIKey
- BBIVCWWQPMOKAC-MSOLQXFVSA-N
- Catalogue number
- GC73998
- Brand
- GLPBIO
Computed properties PubChem CID 156295589 · XLogP 4.7 · TPSA 100 Ų · H-bond donors 0
- XLogP
- 4.7
- TPSA
- 100 Ų
- H-bond donors
- 0
- H-bond acceptors
- 8
- Rotatable bonds
- 3
- Heavy atoms
- 45
SMILES C[C@@H]1CN([C@H](CN1C(=O)C=C)C)C2=NC(=O)N3C4=C(C=CN=C4C(C)C)OCCOC5=C(C=CC(=C5C6=C(C=C2C3=N6)Cl)F)F
Computed descriptors from PubChem (CID 156295589), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il