GC73996
PROTAC AR/AR-V7 degrader-1
Also known as 4-[3-[2-[(8-fluoroquinolin-5-yl)amino]ethyl]-4,4-dimethyl-2,5-dioxoimidazolidin-1-yl]-2-(trifluoromethyl)benzonitrile
PROTAC AR/AR-V7 degrader-1 (27c) is a PROTAC-based and dual AR, AR-V7 degrader, with DC50 values of 2·67 and 2·64 μM for AR and AR-V7, respectively
ChemicalCAS2841308-96-9MW485.43FormulaC24H19F4N5O2
- CAS number
- 2841308-96-9
- Molecular weight
- 485.43
- Formula
- C24H19F4N5O2
- Solubility
- DMSO ： ≥ 100 mg/mL (206·00 mM)
- InChIKey
- QMRZVTDYXXBISG-UHFFFAOYSA-N
- Catalogue number
- GC73996
- Brand
- GLPBIO
Computed properties PubChem CID 162351884 · XLogP 4.1 · TPSA 89.3 Ų · H-bond donors 1
- XLogP
- 4.1
- TPSA
- 89.3 Ų
- H-bond donors
- 1
- H-bond acceptors
- 9
- Rotatable bonds
- 5
- Heavy atoms
- 35
SMILES CC1(C(=O)N(C(=O)N1CCNC2=C3C=CC=NC3=C(C=C2)F)C4=CC(=C(C=C4)C#N)C(F)(F)F)C
Computed descriptors from PubChem (CID 162351884), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il