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Chemical structure of KME-2780

GC73873

KME-2780

Also known as 6-[6-(1-methylcyclopropyl)imidazo[1,2-a]pyridin-3-yl]-N-[(3S)-pyrrolidin-3-yl]pyridin-2-amine

KME-2780 is a potent and selective dual IRAK1 and IRAK4 inhibitor and can be used for research of dysregulation of innate immune signaling and hematologic malignancies

ChemicalCAS2968466-26-2MW333.43FormulaC20H23N5
CAS number
2968466-26-2
Molecular weight
333.43
Formula
C20H23N5
Solubility
DMSO ： 100 mg/mL (299·91 mM; Need ultrasonic)
InChIKey
MQDBFBFFYMGKEJ-HNNXBMFYSA-N
Catalogue number
GC73873
Brand
GLPBIO
Computed properties PubChem CID 169129331 · XLogP 3.9 · TPSA 54.3 Ų · H-bond donors 2
XLogP
3.9
TPSA
54.3 Ų
H-bond donors
2
H-bond acceptors
4
Rotatable bonds
4
Heavy atoms
25

SMILES CC1(CC1)C2=CN3C(=NC=C3C4=NC(=CC=C4)N[C@H]5CCNC5)C=C2

Computed descriptors from PubChem (CID 169129331), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.