Loading...
Chemical structure of HFI-437

GC73861

HFI-437

Also known as ethyl 2-acetamido-7-hydroxy-4-quinolin-3-yl-4H-chromene-3-carboxylate

HFI-437 is a potent non-peptidic insulin-regulated aminopeptidase (IRAP) inhibitor with a Ki of 20 nM

ChemicalCAS1110650-74-2MW404.42FormulaC23H20N2O5
CAS number
1110650-74-2
Molecular weight
404.42
Formula
C23H20N2O5
Solubility
DMSO : 100 mg/mL (247·27 mM; Need ultrasonic)
InChIKey
YOODOXUTKZODHS-UHFFFAOYSA-N
Catalogue number
GC73861
Brand
GLPBIO
Computed properties PubChem CID 42610322 · XLogP 3.6 · TPSA 97.8 Ų · H-bond donors 2
XLogP
3.6
TPSA
97.8 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
5
Heavy atoms
30

SMILES CCOC(=O)C1=C(OC2=C(C1C3=CC4=CC=CC=C4N=C3)C=CC(=C2)O)NC(=O)C

Computed descriptors from PubChem (CID 42610322), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.