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Chemical structure of HFI-142

GC34613

HFI-142

Also known as ethyl 2-amino-7-hydroxy-4-pyridin-3-yl-4H-chromene-3-carboxylate

HFI-142 is an insulin-regulated aminopeptidase (IRAP) inhibitor with a Ki of 2·01 μM

ChemicalCAS332164-34-8MW312.32FormulaC17H16N2O4
CAS number
332164-34-8
Molecular weight
312.32
Formula
C17H16N2O4
Solubility
DMSO : 125 mg/mL (400·23 mM; Need ultrasonic)
InChIKey
JOPNHSIHFSZJMB-UHFFFAOYSA-N
Catalogue number
GC34613
Brand
GLPBIO
Computed properties PubChem CID 655457 · XLogP 2.4 · TPSA 94.7 Ų · H-bond donors 2
XLogP
2.4
TPSA
94.7 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
4
Heavy atoms
23

SMILES CCOC(=O)C1=C(OC2=C(C1C3=CN=CC=C3)C=CC(=C2)O)N

Computed descriptors from PubChem (CID 655457), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
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