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Chemical structure of GSK866

GC73736

GSK866

Also known as 5-amino-N-[(2S)-2-[[(2,6-dichlorobenzoyl)-ethylamino]methyl]-3,3,3-trifluoro-2-hydroxypropyl]-1-(4-fluorophenyl)pyrazole-4-carboxamide

GSK866 is a selective glucocorticoid receptor agonist, with an IC50 of 4·6 nM

ChemicalCAS1991970-93-4MW562.34FormulaC23H21Cl2F4N5O3
CAS number
1991970-93-4
Molecular weight
562.34
Formula
C23H21Cl2F4N5O3
InChIKey
LKQMULLPLYLIGW-QFIPXVFZSA-N
Catalogue number
GC73736
Brand
GLPBIO
Computed properties PubChem CID 25058139 · XLogP 4.6 · TPSA 113 Ų · H-bond donors 3
XLogP
4.6
TPSA
113 Ų
H-bond donors
3
H-bond acceptors
9
Rotatable bonds
8
Heavy atoms
37

SMILES CCN(C[C@@](CNC(=O)C1=C(N(N=C1)C2=CC=C(C=C2)F)N)(C(F)(F)F)O)C(=O)C3=C(C=CC=C3Cl)Cl

Computed descriptors from PubChem (CID 25058139), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.