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Chemical structure of GSK8612

GC65013

GSK8612

Also known as 4-[[[5-bromo-2-[[3-methyl-1-(2,2,2-trifluoroethyl)pyrazol-4-yl]amino]pyrimidin-4-yl]amino]methyl]benzenesulfonamide

GSK8612 is a highly selective and potent Tank-binding Kinase-1 (TBK1) inhibitor, with a pIC50 of 6·8 for recombinant TBK1

ChemicalCAS2361659-62-1MW520.33FormulaC17H17BrF3N7O2S
CAS number
2361659-62-1
Molecular weight
520.33
Formula
C17H17BrF3N7O2S
Solubility
DMSO ： ≥ 125 mg/mL (240·23 mM)
InChIKey
FFPHMUIGESPOTK-UHFFFAOYSA-N
Catalogue number
GC65013
Brand
GLPBIO
Computed properties PubChem CID 137553174 · XLogP 2.9 · TPSA 136 Ų · H-bond donors 3
XLogP
2.9
TPSA
136 Ų
H-bond donors
3
H-bond acceptors
11
Rotatable bonds
7
Heavy atoms
31

SMILES CC1=NN(C=C1NC2=NC=C(C(=N2)NCC3=CC=C(C=C3)S(=O)(=O)N)Br)CC(F)(F)F

Computed descriptors from PubChem (CID 137553174), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.