Loading...
Chemical structure of ACBI3

GC73732

ACBI3

Also known as (2S,4R)-1-[(2S)-2-[4-[4-[(3S)-4-[4-[5-[(4S)-2-amino-3-cyano-4-methyl-6,7-dihydro-5H-1-benzothiophen-4-yl]-1,2,4-oxadiazol-3-yl]pyrimidin-2-yl]-3-methyl-1,4-diazepan-1-yl]butoxy]triazol-1-yl]-3-methylbutanoyl]-4-hydroxy-N-[(1R)-2-hydroxy-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]ethyl]pyrrolidine-2-carboxamide

ACBI3 (compound 7) is a pan-KRAS degrader

ChemicalCAS2938169-76-5MW1019.25FormulaC50H62N14O6S2
CAS number
2938169-76-5
Molecular weight
1019.25
Formula
C50H62N14O6S2
Solubility
DMSO ： 250 mg/mL (245·28 mM; Need ultrasonic)
InChIKey
DQRZNYPHOWVXPQ-YDUPODKQSA-N
Catalogue number
GC73732
Brand
GLPBIO
Computed properties PubChem CID 169449364 · XLogP 6.2 · TPSA 320 Ų · H-bond donors 4
XLogP
6.2
TPSA
320 Ų
H-bond donors
4
H-bond acceptors
19
Rotatable bonds
17
Heavy atoms
72

SMILES C[C@H]1CN(CCCN1C2=NC=CC(=N2)C3=NOC(=N3)[C@]4(CCCC5=C4C(=C(S5)N)C#N)C)CCCCOC6=CN(N=N6)[C@@H](C(C)C)C(=O)N7C[C@@H](C[C@H]7C(=O)N[C@@H](CO)C8=CC=C(C=C8)C9=C(N=CS9)C)O

Computed descriptors from PubChem (CID 169449364), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.