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Chemical structure of ACA-28

GC68597

ACA-28

Also known as [4-[methoxycarbonyloxy(phenyl)methyl]phenyl] methyl carbonate

ACA-28 (compound 2a) is an effective ERK MAPK signaling regulator· ACA-28 induces apoptosis through excessive activation of ERK and selectively inhibits cancer cell growth· ACA-28 inhibits the growth of melanoma cells (SK-MEL-28) and normal melanocytes (NHEM), with IC50 values of 5·3 and 10·1 μM, respectively

ChemicalCAS948044-25-5MW316.31FormulaC17H16O6
CAS number
948044-25-5
Molecular weight
316.31
Formula
C17H16O6
Solubility
DMSO : 100 mg/mL (316·15 mM; Need ultrasonic)
InChIKey
UZLVJKSHIATGCE-UHFFFAOYSA-N
Catalogue number
GC68597
Brand
GLPBIO
Computed properties PubChem CID 44574021 · XLogP 3.9 · TPSA 71.1 Ų · H-bond donors 0
XLogP
3.9
TPSA
71.1 Ų
H-bond donors
0
H-bond acceptors
6
Rotatable bonds
8
Heavy atoms
23

SMILES COC(=O)OC1=CC=C(C=C1)C(C2=CC=CC=C2)OC(=O)OC

Computed descriptors from PubChem (CID 44574021), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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