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Chemical structure of WRN inhibitor 5

GC73664

WRN inhibitor 5

Also known as N-[(3R)-1,1-dioxo-2,3-dihydrothiophen-3-yl]-5-hydroxy-2-oxo-6-(2-phenylmethoxyphenyl)-1H-pyridine-3-carboxamide

WRN inhibitor 5 (example 157), a cyclic vinyl sulfone compound, is a Wemer Syndrome ATP dependent helicase enzyme (WRN) inhibitor

ChemicalCAS2923009-95-2MW452.48FormulaC23H20N2O6S
CAS number
2923009-95-2
Molecular weight
452.48
Formula
C23H20N2O6S
Solubility
DMSO ： 100 mg/mL (221·00 mM; ultrasonic and warming and heat to 60°C)
InChIKey
UATCHQZLFRSLIK-MRXNPFEDSA-N
Catalogue number
GC73664
Brand
GLPBIO
Computed properties PubChem CID 168205573 · XLogP 1.6 · TPSA 130 Ų · H-bond donors 3
XLogP
1.6
TPSA
130 Ų
H-bond donors
3
H-bond acceptors
6
Rotatable bonds
6
Heavy atoms
32

SMILES C1[C@@H](C=CS1(=O)=O)NC(=O)C2=CC(=C(NC2=O)C3=CC=CC=C3OCC4=CC=CC=C4)O

Computed descriptors from PubChem (CID 168205573), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.