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Chemical structure of KY386

GC73638

KY386

Also known as 1-(3-cyano-5-methylthiophen-2-yl)-N-(6-methoxy-1H-benzimidazol-2-yl)-2,5-dimethylpyrrole-3-carboxamide

KY386 is a potent, selective inhibitor of DHX33 helicase, with the IC50 of 19 nM

ChemicalCAS2787598-01-8MW405.47FormulaC21H19N5O2S
CAS number
2787598-01-8
Molecular weight
405.47
Formula
C21H19N5O2S
Solubility
DMSO ： 100 mg/mL (246·63 mM; Need ultrasonic)
InChIKey
HGIMQJMGWCFYPE-UHFFFAOYSA-N
Catalogue number
GC73638
Brand
GLPBIO
Computed properties PubChem CID 166058639 · XLogP 4 · TPSA 124 Ų · H-bond donors 2
XLogP
4
TPSA
124 Ų
H-bond donors
2
H-bond acceptors
5
Rotatable bonds
4
Heavy atoms
29

SMILES CC1=CC(=C(N1C2=C(C=C(S2)C)C#N)C)C(=O)NC3=NC4=C(N3)C=C(C=C4)OC

Computed descriptors from PubChem (CID 166058639), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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