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Chemical structure of KY19382

GC60970

KY19382

Also known as 5,6-dichloro-3-[(3Z)-3-methoxyiminoindol-2-yl]-1H-indol-2-ol

KY19382 is a potent and orally active dual inhibitor of CXXC5-DVL and GSK3β, with IC50s of 19 and 10 nM, respectively

ChemicalCAS2226664-93-1MW360.19FormulaC17H11Cl2N3O2
CAS number
2226664-93-1
Molecular weight
360.19
Formula
C17H11Cl2N3O2
Solubility
DMSO: 5 mg/mL (13·88 mM)
InChIKey
TVZDUDDLASVAOM-JCMHNJIXSA-N
Catalogue number
GC60970
Brand
GLPBIO
Computed properties PubChem CID 148959784 · XLogP 4.6 · TPSA 70 Ų · H-bond donors 2
XLogP
4.6
TPSA
70 Ų
H-bond donors
2
H-bond acceptors
4
Rotatable bonds
2
Heavy atoms
24

SMILES CO/N=C\1/C2=CC=CC=C2N=C1C3=C(NC4=CC(=C(C=C43)Cl)Cl)O

Computed descriptors from PubChem (CID 148959784), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.