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Chemical structure of PF-07202954

GC73626

PF-07202954

Also known as 2-[5-[(3-ethoxy-2-pyridinyl)oxy]-3-pyridinyl]-N-[(3S,5S)-5-fluoropiperidin-3-yl]pyrimidine-5-carboxamide

PF-07202954 is a weakly basic DGAT2 inhibitor with an IC50 of 10 nM for human DGAT2

ChemicalCAS2639372-47-5MW438.45FormulaC22H23FN6O3
CAS number
2639372-47-5
Molecular weight
438.45
Formula
C22H23FN6O3
Solubility
DMSO : 3·33 mg/mL (7·59 mM; ultrasonic and warming and heat to 60°C)
InChIKey
CPBXJSPVZIPJMX-IRXDYDNUSA-N
Catalogue number
GC73626
Brand
GLPBIO
Computed properties PubChem CID 146422953 · XLogP 1.4 · TPSA 111 Ų · H-bond donors 2
XLogP
1.4
TPSA
111 Ų
H-bond donors
2
H-bond acceptors
9
Rotatable bonds
7
Heavy atoms
32

SMILES CCOC1=C(N=CC=C1)OC2=CN=CC(=C2)C3=NC=C(C=N3)C(=O)N[C@H]4C[C@@H](CNC4)F

Computed descriptors from PubChem (CID 146422953), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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