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Chemical structure of YK-029A

GC73582

YK-029A

Also known as N-[2-[2-(dimethylamino)ethyl-methylamino]-4-methoxy-5-[[4-(8-methylimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]amino]phenyl]prop-2-enamide

YK-029A is an orally active inhibitor of mutant EGFR,targeting to both the T790M mutations (EGFRT790M) and exon 20 insertion of EGFR (EGFRex20ins)

ChemicalCAS2064269-82-3MW500.6FormulaC27H32N8O2
CAS number
2064269-82-3
Molecular weight
500.6
Formula
C27H32N8O2
Solubility
DMSO ： 100 mg/mL (199·76 mM; Need ultrasonic)
InChIKey
OEFWUILIMFIVSE-UHFFFAOYSA-N
Catalogue number
GC73582
Brand
GLPBIO
Computed properties PubChem CID 154593283 · XLogP 3.9 · TPSA 99.9 Ų · H-bond donors 2
XLogP
3.9
TPSA
99.9 Ų
H-bond donors
2
H-bond acceptors
8
Rotatable bonds
10
Heavy atoms
37

SMILES CC1=CC=CN2C1=NC=C2C3=NC(=NC=C3)NC4=C(C=C(C(=C4)NC(=O)C=C)N(C)CCN(C)C)OC

Computed descriptors from PubChem (CID 154593283), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.