Loading...
Chemical structure of PARP7-IN-15

GC73566

PARP7-IN-15

Also known as 4-[(2S)-2-[[3-oxo-3-[(10S)-5-(trifluoromethyl)-8-oxa-1,3,12-triazatricyclo[8.4.0.02,7]tetradeca-2(7),3,5-trien-12-yl]propoxy]methyl]azetidin-1-yl]-5-(trifluoromethyl)-1H-pyridazin-6-one

PARP7-IN-15 (Compound 18) is a PARP7 inhibitor with IC50 of 0·56 nM, that has antitumor activity

ChemicalCAS2819998-97-3MW562.46FormulaC23H24F6N6O4
CAS number
2819998-97-3
Molecular weight
562.46
Formula
C23H24F6N6O4
Solubility
DMSO ： 200 mg/mL (355·58 mM; Need ultrasonic)
InChIKey
BANSZVBMEHYKAV-GJZGRUSLSA-N
Catalogue number
GC73566
Brand
GLPBIO
Computed properties PubChem CID 167242318 · XLogP 1.5 · TPSA 99.6 Ų · H-bond donors 1
XLogP
1.5
TPSA
99.6 Ų
H-bond donors
1
H-bond acceptors
14
Rotatable bonds
6
Heavy atoms
39

SMILES C1CN([C@@H]1COCCC(=O)N2CCN3[C@@H](C2)COC4=C3N=CC(=C4)C(F)(F)F)C5=C(C(=O)NN=C5)C(F)(F)F

Computed descriptors from PubChem (CID 167242318), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.