GC64579
PARP-1-IN-2
Also known as N-(3-chlorophenyl)-2-[4-(4-chlorophenyl)-1-oxophthalazin-2-yl]acetamide
PARP-1-IN-2 (compound 11g) is a potent and BBB-penetrated PARP1 inhibitor, with an IC50 of 149 nM· PARP1-IN-2 shows significantly potent anti-proliferative activity against Human lung adenocarcinoma epithelial cell line A549· PARP1-IN-2 can induce A549 cells apoptosis
ChemicalCAS684234-55-7MW424.28FormulaC22H15Cl2N3O2
- CAS number
- 684234-55-7
- Molecular weight
- 424.28
- Formula
- C22H15Cl2N3O2
- Solubility
- DMSO ： 83·33 mg/mL (196·40 mM; Need ultrasonic)
- InChIKey
- ASIIOGZHCMSESG-UHFFFAOYSA-N
- Catalogue number
- GC64579
- Brand
- GLPBIO
Computed properties PubChem CID 1987353 · XLogP 5 · TPSA 61.8 Ų · H-bond donors 1
- XLogP
- 5
- TPSA
- 61.8 Ų
- H-bond donors
- 1
- H-bond acceptors
- 3
- Rotatable bonds
- 4
- Heavy atoms
- 29
SMILES C1=CC=C2C(=C1)C(=NN(C2=O)CC(=O)NC3=CC(=CC=C3)Cl)C4=CC=C(C=C4)Cl
Computed descriptors from PubChem (CID 1987353), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il