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Chemical structure of SRX3177

GC73504

SRX3177

Also known as 7-cyclopentyl-N,N-dimethyl-2-[4-(5-morpholin-4-yl-7-oxothieno[3,2-b]pyran-3-yl)anilino]pyrrolo[2,3-d]pyrimidine-6-carboxamide

SRX3177 is a triple inhibitor of CDK4/6, PI3K, and BRD4, with IC50s of 33 nM (BRD4 BD1), 89 nM (BRD4 BD2), 79 nM (PI3Kα), 83 nM (PI3Kδ), 3·18 μM (PI3Kγ), ＜2·5 nM (CDK4), 3·3 nM (CDK6), respectively

ChemicalCAS2241237-51-2MW584.69FormulaC31H32N6O4S
CAS number
2241237-51-2
Molecular weight
584.69
Formula
C31H32N6O4S
Solubility
DMSO ： 25 mg/mL (42·76 mM; Need ultrasonic)
InChIKey
XJKTXWSMMWPNTP-UHFFFAOYSA-N
Catalogue number
GC73504
Brand
GLPBIO
Computed properties PubChem CID 153289441 · XLogP 4.7 · TPSA 130 Ų · H-bond donors 1
XLogP
4.7
TPSA
130 Ų
H-bond donors
1
H-bond acceptors
9
Rotatable bonds
6
Heavy atoms
42

SMILES CN(C)C(=O)C1=CC2=CN=C(N=C2N1C3CCCC3)NC4=CC=C(C=C4)C5=CSC6=C5OC(=CC6=O)N7CCOCC7

Computed descriptors from PubChem (CID 153289441), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.