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Chemical structure of WM-586

GC73478

WM-586

Also known as 3-[3,5-difluoro-4-[(2S)-2-(2H-tetrazol-5-ylcarbamoyl)hexyl]phenyl]benzenesulfonyl fluoride

WM-586 is a covalent WDR5 inhibitor that disrupts the binding of WDR5 to MYC

ChemicalCAS2894832-05-2MW467.46FormulaC20H20F3N5O3S
CAS number
2894832-05-2
Molecular weight
467.46
Formula
C20H20F3N5O3S
InChIKey
BWWWIQSHXJUWBT-ZDUSSCGKSA-N
Catalogue number
GC73478
Brand
GLPBIO
Computed properties PubChem CID 167312325 · XLogP 4.5 · TPSA 126 Ų · H-bond donors 2
XLogP
4.5
TPSA
126 Ų
H-bond donors
2
H-bond acceptors
9
Rotatable bonds
9
Heavy atoms
32

SMILES CCCC[C@@H](CC1=C(C=C(C=C1F)C2=CC(=CC=C2)S(=O)(=O)F)F)C(=O)NC3=NNN=N3

Computed descriptors from PubChem (CID 167312325), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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