Loading...
Chemical structure of JS11

GC73468

JS11

Also known as 1-cyclohexyl-3-(cyclopropylmethyl)-N-[(3-methyl-1,2-oxazol-5-yl)methyl]-2-oxobenzimidazole-5-carboxamide

JS11 is an inhibitor for natriuretic polypeptide receptor 1 (Npr1) with an IC50 of 1·9 μM for hNpr1

ChemicalCAS1394592-04-1MW408.49FormulaC23H28N4O3
CAS number
1394592-04-1
Molecular weight
408.49
Formula
C23H28N4O3
Solubility
DMSO ： 50 mg/mL (122·40 mM; ultrasonic and warming and heat to 60°C)
InChIKey
OHSMTKLVCHFYEF-UHFFFAOYSA-N
Catalogue number
GC73468
Brand
GLPBIO
Computed properties PubChem CID 70756727 · XLogP 3.1 · TPSA 78.7 Ų · H-bond donors 1
XLogP
3.1
TPSA
78.7 Ų
H-bond donors
1
H-bond acceptors
4
Rotatable bonds
6
Heavy atoms
30

SMILES CC1=NOC(=C1)CNC(=O)C2=CC3=C(C=C2)N(C(=O)N3CC4CC4)C5CCCCC5

Computed descriptors from PubChem (CID 70756727), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.