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Chemical structure of PROTAC BRD9 Degrader-6

GC73466

PROTAC BRD9 Degrader-6

Also known as 3-[5-[7-[[1-[[4-[6-(azetidin-1-yl)-2-methyl-1-oxo-2,7-naphthyridin-4-yl]-2,6-dimethoxyphenyl]methyl]piperidin-4-yl]methyl]-2,7-diazaspiro[3.5]nonan-2-yl]-3-oxo-1H-isoindol-2-yl]piperidine-2,6-dione

PROTAC BRD9 Degrader-6 is a potent degrader of BRD9 (IC50=0·13 nM), can be used for research of BAF complex-related disorders

ChemicalCAS2676211-62-2MW829FormulaC47H56N8O6
CAS number
2676211-62-2
Molecular weight
829
Formula
C47H56N8O6
Solubility
DMSO : 100 mg/mL (120·63 mM; Need ultrasonic)
InChIKey
OBNRBCUHEAAFPS-UHFFFAOYSA-N
Catalogue number
GC73466
Brand
GLPBIO
Computed properties PubChem CID 156817976 · XLogP 3.2 · TPSA 131 Ų · H-bond donors 1
XLogP
3.2
TPSA
131 Ų
H-bond donors
1
H-bond acceptors
11
Rotatable bonds
10
Heavy atoms
61

SMILES CN1C=C(C2=CC(=NC=C2C1=O)N3CCC3)C4=CC(=C(C(=C4)OC)CN5CCC(CC5)CN6CCC7(CC6)CN(C7)C8=CC9=C(CN(C9=O)C1CCC(=O)NC1=O)C=C8)OC

Computed descriptors from PubChem (CID 156817976), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.