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Chemical structure of PPI-GIT1/β-Pix interaction-IN-1

GC73381

PPI-GIT1/β-Pix interaction-IN-1

Also known as ethyl (1S,2R,3R,4S,5E)-5-(furan-3-ylmethylidene)-1'-methyl-2',6-dioxospiro[bicyclo[2.2.1]heptane-3,3'-indole]-2-carboxylate

PPI-GIT1/β-Pix interaction-IN-1 is a potent and orally active GIT1/β-Pix protein-protein interaction (PPI) inhibitor with a KD value of 7·7 µM

ChemicalCAS2070916-70-8MW391.42FormulaC23H21NO5
CAS number
2070916-70-8
Molecular weight
391.42
Formula
C23H21NO5
Solubility
DMSO ： 100 mg/mL (255·48 mM; Need ultrasonic)
InChIKey
RLZMEKDCXNWDNP-ORQQMLAUSA-N
Catalogue number
GC73381
Brand
GLPBIO
Computed properties PubChem CID 122707028 · XLogP 1.9 · TPSA 76.8 Ų · H-bond donors 0
XLogP
1.9
TPSA
76.8 Ų
H-bond donors
0
H-bond acceptors
5
Rotatable bonds
4
Heavy atoms
29

SMILES CCOC(=O)[C@@H]1[C@@H]2C[C@H]([C@]13C4=CC=CC=C4N(C3=O)C)/C(=C\C5=COC=C5)/C2=O

Computed descriptors from PubChem (CID 122707028), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.