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Chemical structure of CDK8-IN-11

GC73345

CDK8-IN-11

Also known as 1-[4-[(6-amino-3-pyridinyl)oxy]phenyl]-3-[3-(trifluoromethyl)phenyl]urea

CDK8-IN-11 is a potent and selective CDK8 inhibitor with an IC50 value of 46 nM

ChemicalCAS2839338-28-0MW388.34FormulaC19H15F3N4O2
CAS number
2839338-28-0
Molecular weight
388.34
Formula
C19H15F3N4O2
Solubility
DMSO ： 250 mg/mL (643·77 mM; Need ultrasonic)
InChIKey
MBIXOXMOHXFUFZ-UHFFFAOYSA-N
Catalogue number
GC73345
Brand
GLPBIO
Computed properties PubChem CID 165412810 · XLogP 3.5 · TPSA 89.3 Ų · H-bond donors 3
XLogP
3.5
TPSA
89.3 Ų
H-bond donors
3
H-bond acceptors
7
Rotatable bonds
4
Heavy atoms
28

SMILES C1=CC(=CC(=C1)NC(=O)NC2=CC=C(C=C2)OC3=CN=C(C=C3)N)C(F)(F)F

Computed descriptors from PubChem (CID 165412810), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.