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Chemical structure of CDK8-IN-12

GC73183

CDK8-IN-12

Also known as 8-[3-(1-benzofuran-2-yl)-5-chloro-4-pyridinyl]-2,8-diazaspiro[4.5]decan-1-one

CDK8-IN-12 is an orally active, potent CDK8 inhibitor with a Ki of 14 nM

ChemicalCAS2613307-67-6MW381.86FormulaC21H20ClN3O2
CAS number
2613307-67-6
Molecular weight
381.86
Formula
C21H20ClN3O2
Solubility
DMSO ： 66·67 mg/mL (174·59 mM; Need ultrasonic)
InChIKey
ILMHDRGZABQLEW-UHFFFAOYSA-N
Catalogue number
GC73183
Brand
GLPBIO
Computed properties PubChem CID 162643699 · XLogP 3.4 · TPSA 58.4 Ų · H-bond donors 1
XLogP
3.4
TPSA
58.4 Ų
H-bond donors
1
H-bond acceptors
4
Rotatable bonds
2
Heavy atoms
27

SMILES C1CNC(=O)C12CCN(CC2)C3=C(C=NC=C3C4=CC5=CC=CC=C5O4)Cl

Computed descriptors from PubChem (CID 162643699), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.