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Chemical structure of SR10221

GC73303

SR10221

Also known as (2S)-2-[5-[[5-[[(1S)-1-(4-tert-butylphenyl)ethyl]carbamoyl]-2,3-dimethylindol-1-yl]methyl]-2-chlorophenoxy]propanoic acid

SR10221, a noncovalent inverse agonist of PPARγ, represses downstream PPARγ target genes leading to growth inhibition in bladder cancer cell lines

ChemicalCAS1415321-64-0MW561.11FormulaC33H37ClN2O4
CAS number
1415321-64-0
Molecular weight
561.11
Formula
C33H37ClN2O4
Solubility
DMSO ： 125 mg/mL (222·77 mM; Need ultrasonic)
InChIKey
NPMSSJHJPGMEJW-UNMCSNQZSA-N
Catalogue number
GC73303
Brand
GLPBIO
Computed properties PubChem CID 71075102 · XLogP 7.8 · TPSA 80.6 Ų · H-bond donors 2
XLogP
7.8
TPSA
80.6 Ų
H-bond donors
2
H-bond acceptors
4
Rotatable bonds
9
Heavy atoms
40

SMILES CC1=C(N(C2=C1C=C(C=C2)C(=O)N[C@@H](C)C3=CC=C(C=C3)C(C)(C)C)CC4=CC(=C(C=C4)Cl)O[C@@H](C)C(=O)O)C

Computed descriptors from PubChem (CID 71075102), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.