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Chemical structure of SR121566A

GC31993

SR121566A

Also known as 3-[[4-(4-carbamimidoylphenyl)-1,3-thiazol-2-yl]-[1-(carboxymethyl)piperidin-4-yl]amino]propanoic acid

SR121566A is a novel non-peptide Glycoprotein IIb/IIIa (GP IIb-IIIa) antagonist, which can inhibit ADP-, arachidonic acid- and collagen-induced human platelet aggregation with IC50s of 46±7·5, 56±6 and 42±3 nM, respectively

ChemicalCAS180144-61-0MW431.51FormulaC20H25N5O4S
CAS number
180144-61-0
Molecular weight
431.51
Formula
C20H25N5O4S
Solubility
Soluble in DMSO
InChIKey
LYIQNVKSTSEEEG-UHFFFAOYSA-N
Catalogue number
GC31993
Brand
GLPBIO
Computed properties PubChem CID 9867414 · XLogP -0.6 · TPSA 172 Ų · H-bond donors 4
XLogP
-0.6
TPSA
172 Ų
H-bond donors
4
H-bond acceptors
9
Rotatable bonds
9
Heavy atoms
30

SMILES C1CN(CCC1N(CCC(=O)O)C2=NC(=CS2)C3=CC=C(C=C3)C(=N)N)CC(=O)O

Computed descriptors from PubChem (CID 9867414), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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Documents
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