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Chemical structure of TH-6

GC73212

TH-6

Also known as 5-fluoro-N-[[3-[(E)-3-(hydroxyamino)-3-oxoprop-1-enyl]-4-methoxyphenyl]methyl]-2-morpholin-4-ylbenzamide

TH-6 is a potent HDAC inhibitor with IC50s of 0·115, 0·135, 0·242, 0·138, 2·120 µM for HDAC1, HDAC2, HDAC3, HDAC6, HDAC8, respectively

ChemicalCAS3031349-25-1MW429.44FormulaC22H24FN3O5
CAS number
3031349-25-1
Molecular weight
429.44
Formula
C22H24FN3O5
Solubility
DMSO ： 50 mg/mL (116·43 mM; ultrasonic and warming and heat to 60°C)
InChIKey
ICQRPCMAJHVDPX-XVNBXDOJSA-N
Catalogue number
GC73212
Brand
GLPBIO
Computed properties PubChem CID 164887552 · XLogP 1.7 · TPSA 100 Ų · H-bond donors 3
XLogP
1.7
TPSA
100 Ų
H-bond donors
3
H-bond acceptors
7
Rotatable bonds
7
Heavy atoms
31

SMILES COC1=C(C=C(C=C1)CNC(=O)C2=C(C=CC(=C2)F)N3CCOCC3)/C=C/C(=O)NO

Computed descriptors from PubChem (CID 164887552), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.